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KMID : 0381219720040030184
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Journal of RIMSK
1972 Volume.4 No. 3 p.184 ~ p.189
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RADIOACTIVE ISOTOPES IN ORTHOPUDIC SURGERY
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Abstract
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The use of radioactive isotopes in the investigation and the treatment of orthopedic conditions, although still in its early stage, promises unlimited possibilities of development.
The following material is offered as a general basis for study by the orthopedic, doctor
that will elicit some interest in this fascinating new field. To physicians, radioactive isotopes are important in 3 ways: (1) as agents of disease: (2) as tracers in biochemical investigations, especially metabolic studies; and (3) as tools in the diagnosis and the treatment of illnesses.
These 3 facets will be considered separately, after a brief description of thy fields of treatment and their properties.
The successful use of radioactive colloidal gold (Au´98) in the treatment of malignant peritoneal and pleural effusions prompted its trial use in cases of persistent synovial effusion in which orthodox methods have consistently failed.
A trial was carried out in 11 patients with persistent effusions.
The injections were given intra-particularly. Follow-up study ranging from 5 months to 5 and half years showed one failure. Pain was almost always relieved and movement facilitated. No complications, either immediate or delayed, occurred as the result of the injections.
The 10cm dose used was estimated on the assumption of the surface area of the synovium. The clinical success of the method would suggest that this dose is adequate to relieve effusion.
The aim of the procedure described here is not to produce a dry joint, or a radiation synovectomy, but only to reduce the excessive accumulation of fluid in the, joint. The injection of a radioactive isotope into a closed cavity is a surface radiation technique.
It allows a high radiation dose with a specific effect on the synovium and with little effect on other tissues. The success of intra-particular radioactive gold in treating chronic effusions in the major joint has proved effective and safe during the 5 and half years in which it has been used.
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KEYWORD
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